Benzenemethanamine, 4-chloro-α,3-dimethyl-, (αS)-

Benzenemethanamine, 4-chloro-α,3-dimethyl-, (αS)- - Names and Identifiers

Name	(1S)-1-(4-chloro-3-methyl-phenyl)ethanamine
Synonyms	LogP 4-chloro-a (1s)-1-(4-chloro-3-methylphenyl)ethanamine (1S)-1-(4-chloro-3-methyl-phenyl)ethanamine (S)-1-(4-CHLORO-3-METHYLPHENYL)ETHANAMINE-HCl Benzenemethanamine, 4-chloro-α,3-dimethyl-, (αS)- Benzenemethanamine, 4-chloro-a,3-dimethyl-, (aS)- (S)-1-(4-Chloro-3-Methylphenyl)ethanaMine hydrochloride (1S)-1-(4-chloro-3-methylphenyl)ethan-1-amine hydrochloride Benzenemethanamine, 4-chloro-.alpha.,3-dimethyl-, (.alpha.S)-
CAS	943760-74-5
InChI	InChI=1/C9H12ClN/c1-6-5-8(7(2)11)3-4-9(6)10/h3-5,7H,11H2,1-2H3/t7-/m0/s1

Benzenemethanamine, 4-chloro-α,3-dimethyl-, (αS)- - Physico-chemical Properties

Molecular Formula	C9H12ClN
Molar Mass	169.654
Density	1.095g/cm³
Boling Point	245.178°C at 760 mmHg
Flash Point	117.811°C
Vapor Presure	0.029mmHg at 25°C
Refractive Index	1.546

Benzenemethanamine, 4-chloro-α,3-dimethyl-, (αS)- - Introduction

(1S)-1-(4-chloro-3-methyl-phenyl)ethanamine ((1S)-1-(4-chloro-3-methyl-phenyl)ethanamine) is an organic compound. Its chemical formula is C10H14ClN, and its appearance is colorless to light yellow liquid or crystal. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow liquid or crystal
-Molecular weight: 187.68g/mol
-Melting point: 60-64 ℃
-Boiling point: 90-95 ℃
-Density: 1.049g/cm³
-Solubility: Soluble in organic solvents, slightly soluble in water

Use:
-In organic synthesis, this compound can be used as a precursor or intermediate to prepare other compounds.
-In the field of medicine, it is also used in the synthesis of certain drugs.

Method:
(1S)-1-(4-chloroo-3-methyl-phenyl) ethanamine can be prepared by the following steps:
1. 4-chloro-3-methylbenzaldehyde reacts with sodium bisulfite and methanol at room temperature to generate 4-chloro-3-methylbenzyl alcohol.
2. 4-chloro-3-methylbenzyl alcohol and o-methylaniline are heated to react in the presence of sulfuric acid to generate (1S)-1-(4-chloroo-3-methyl-phenyl) ethanamine.

Safety Information:
-The compound should be handled with caution and avoid contact with skin and eyes.
-Wear protective gloves, goggles and protective clothing during operation.
-Avoid inhaling gases, dust or haze from the compound.
-If necessary, operate in a well-ventilated place.
-Store it in a sealed container, away from fire and oxidizing agents.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice.
-For detailed safety information on this compound, please refer to the relevant safety data sheet.

Last Update：2024-04-09 20:02:46